• Home
  • Research
    • Neuroblastoma Research >
      • Chromosomal copy number alterations as smoking guns for new therapeutic targets in neuroblastoma
      • Novel combination therapies targeting replication stress resistance and DNA damage repair
      • Targeted protein degradation - PROTAC development
      • ingle-cell and spatial multi-omics mapping of immunomodulatory drug responses
    • PEDIATRIC SARCOMA RESEARCH
    • Patient Avatar Models
  • Publications
  • News
  • People
  • Donate
  • Contact
  • Home
  • Research
    • Neuroblastoma Research >
      • Chromosomal copy number alterations as smoking guns for new therapeutic targets in neuroblastoma
      • Novel combination therapies targeting replication stress resistance and DNA damage repair
      • Targeted protein degradation - PROTAC development
      • ingle-cell and spatial multi-omics mapping of immunomodulatory drug responses
    • PEDIATRIC SARCOMA RESEARCH
    • Patient Avatar Models
  • Publications
  • News
  • People
  • Donate
  • Contact

Our research focus

NEUROBLASTOMA AND SARCOMA RESEARCH
​Childhood cancers are rare and have high overall survival, but remain the first cause of death from disease in children.  Our team focuses on neuroblastoma and pediatric sarcoma to advance our understanding of the development of these tumor types in children
PEDIATRIC PRECISION ONCOLOGY
We scrutinize the molecular basis of neuroblastoma and pediatric sarcomas to deliver novel entry points for a precision oncology approach, both by drug repurposing and de novo drug development efforts.
​patient avatar models
We also strongly invest in the development of in vivo patient derived avatar models that enable the evaluation of a personalized treatment strategy. ​

PPOL is part of the CRIG network in Ghent

Picture
One in three men and one in four women in Belgium are diagnosed with cancer before the age of 75. Despite important successes during the last decades, the mechanisms underlying the development and progression of cancer are only partially understood. Hence, cancer researchers are facing great challenges in their quest for better and targeted treatments.

Ghent University (UGent), Ghent University Hospital (UZ Gent) and VIB-UGent (a life sciences research institute in Flanders), have a strong history concerning cancer research. Over the years, different research teams acquired specific expertise that resulted in internationally renowned cancer research. In addition, clinical applications of novel treatments and diagnostic and prognostic tests were implemented. Many research activities and knowhow are however scattered over diverse campuses of UGent, UZ Gent and VIB-UGent. 
CRIG's mission is to unite, stimulate and enhance the impact of cancer research at Ghent University, Ghent University Hospital and VIB-UGent.

Learn more about CRIG by visiting their website HERE.

​ 

Pediatric Precision Oncology Lab Ghent

Understanding childhood cancer
​development for better cures


Donate

Medical Research Building (MRB), 2nd floor
Corneel Heymanslaan 10, B-9000 Ghent, Belgium
​

Tel: +32 9 332 55 33
Email: [email protected]
PPOL lab © 2024
  • Home
  • Research
    • Neuroblastoma Research >
      • Chromosomal copy number alterations as smoking guns for new therapeutic targets in neuroblastoma
      • Novel combination therapies targeting replication stress resistance and DNA damage repair
      • Targeted protein degradation - PROTAC development
      • ingle-cell and spatial multi-omics mapping of immunomodulatory drug responses
    • PEDIATRIC SARCOMA RESEARCH
    • Patient Avatar Models
  • Publications
  • News
  • People
  • Donate
  • Contact