Single-cell and spatial multi-omics mapping of immunomodulatory drug responses
In recent years, considerable research effort has been focused across multiple tumor types on understanding how the tumor immune microenvironment (TIME) can be altered to promote cancer cell recognition and elimination.
Implementation of immunotherapy has been challenging in neuroblastoma, as these tumors are considered immunologically “cold” tumors, presenting with only limited lymphocyte infiltration.
In our lab we are further exploring how we can 'heat up' the neuroblastoma tumor immune micro-environment.
For this project, we are part of the GOA consortium, collaborating with different research groups from the UGent.
Implementation of immunotherapy has been challenging in neuroblastoma, as these tumors are considered immunologically “cold” tumors, presenting with only limited lymphocyte infiltration.
In our lab we are further exploring how we can 'heat up' the neuroblastoma tumor immune micro-environment.
For this project, we are part of the GOA consortium, collaborating with different research groups from the UGent.
